My husband and i have lived in 6 different places, in 6 six years of marriage thank you army, and everywhere we have lived, we have kept an aloe vera plant in the yard or in a pot. Aloe gel is put to the test headtohead versus steroids against the chronic inflammatory skin disease psoriasis. Aloe vera could prevent adjuvant arthritis 72%, and cause a regression of 22 to 26% at a dosage of 150 mgkg per day. Aloe vera shows antimicrobial activity by rupturing bacterial cell walls.
The aim of this study was to evaluate the antifungal and antioxidant activities of the leaf extract. Microencapsulation of natural antioxidant powder from aloe. The objective of this study was to determine and compare the antioxidant activity of aloe vera of different growth periods and their extracts with bht and r. Evaluation of antiinflammatory and analgesic effects on. Chemical composition and antioxidant activity of tannins. Creston collins having seen the seminole indians using the leaf of the plant to treat burns. Aloe vera has been used worldwide for pharmaceutical, food, and cosmetic industries due to of its wide biological activities. In vitro and in vivo antioxidant activities of polysaccharide. This article is confined to literature pertaining to aloe vera. Aloe vera, wound healing, periodontal health, antidiabetic activity.
Enzymatic extracts were prepared from aloe vera gel by using ten digestive enzymes including. Aloe vera facts, health benefits and nutritional value. Woundhealing via cell proliferation and migration 28. Independent testing proves that natural approach aloe vera increases cell activity by over 50%. The healing effect of aloe results from its ability to prevent injury to epithelial tissues, and promote healing of injured tissues. Aloe vera extract as a promising treatment for the quality. Antimicrobial activity of four extracts was performed by agar well diffusion method against different bacteria and fungi.
Aloe vera is well known for its marvelous medicinal properties. Oh, c h and co have been detected as predominant functional group. Aloe vera polysaccharide antioxidant both activity zebra. Aloe vera had a dosedependent inhibitory effect on reactive oxygen metabolite production, and it also inhibited the production of prostaglandin e 2 by 30% at a 1 in 50 dilution p 0. The implication of unguided human consumption of a. Aloe is processed using the handfilleted or whole leaf procedure. Typically, aloe vera products should contain a significant quantity of aloe vera in the formula 30%. Careful processing of aloe gel is necessary to maintain activity. Medical usage and applications of the main species, namely aloe vera l. Medicinal applications and toxicological activities of aloe. Antihyperlipidemic activity aloe vera has been shown to prevent fatty streak development and also reduce the development of atherosclerosis through the modification of high risk factors. Immune system balance pdf natural products insider all eyes on aloe pdf lewis je, mcdaniel hr, et. Oh, c h and co have been detected as predominant functional group phenolic oh attributes to antioxidant activity of methanolic extract of gel.
Negative effects of aloe vera gel on paracetamolinduced. Aloe vera aloe barbadensis miller is a perennial plant of the xanthorrhoeaceae family united, 2012. It is called the healing plant or the silent healer because of its wound and burn healing properties. Aloe vera, antimicrobial activities, antioxidant activities, antitumor. Pdf antioxidant activity of true aloe aloe vera extract.
Improved chromatographic methods for determination of. Evaluation of antioxidant potential of aloe vera aloe. Antioxidant and antityrosinase activities of aloe vera. It is proved by the present study that, seed extract at the dose of 500 mgkg possesses a maximum activity 80. Collins 2 first became interested in the therapeutic use of the leaves in 1935, his son dr. Methods already published were used as a starting point for the development of the new method. Sonya bonifacia mahadi et al antioxidant and antityrosinase activities of aloe vera rind and gel extracts global medical and health communication, volume 7 number 3, december 2019 176. Aloe barbadensis miller, aloe vera, has a long history of use as a topical and oral therapeutic mary d. Aruna devaraj2 1department of biochemistry, shrimati indira gandhi college, tiruchirappalli, tamilnadu, india. Aloe vera, medicine plant, food additive introduction for centuries, aloe vera has been used by many different.
Proximate composition moisture, ash, crude protein, crude lipid and crude fibre, ascorbic acid, superoxide dismutase, catalase, peroxidase, amylase. In this work three chromatographic methods were developed to reduce the total time of the analysis of main compounds in aloe vera extracts. In another experiment, we proved that aloe vera was effective in reducing inflammation over a broad spectrum of irritants in experimental animals. Germplasm ic112517 showed maximum gel percentage 97. Since 1930, aloe vera gel has been used in clinical practices.
Aloe vera is approved by the food and drug administration as a food additive for flavor. The threeyearold extract exhibited the strongest radical scavenging activity of 72. Aloe vera has been used in traditional medicine because it contains several bioactive compounds that act as antioxidant and prevent aging process. D a glycoprotein, g1g1m1di2, was isolated from aloe vera. Aloe vera is found as the wild herb along the coast. The innermost part of the leaf is a clear, soft, moist, and slippery tissue that consists of large thinwalled parenchyma cells in which water is held in the. Before that, analysis of aloe vera gel revealed that it has glucomannans, acemmanan, carboxypeptidase, salicylates, and thromboxane inhibitors. In writings of chinese and indian early cultures, references have been found. Aloe vera help to soothe skin injuries affected by burning, skin irritations, cuts and insect bites, and its bactericidal properties relieve itching and skin swellings. Antibacterial activity of aloe vera the antibacterial studies were carried out by disc diffusion technique 20. Aloe vera linne or aloe barbadensis miller is a succulent from the aloe family 400 different species with its origin in african continent. Enzymatic extracts were prepared from aloe vera gel.
The healthy effect of aloe vera is primarily attributed to the polysaccharides contained in the gel of the leaves. We also studied the capacity of the aqueous extract to inhibit cyclooxygenase activity. Preparation of aloe vera gel extract aloe vera powder was prepared from aloe vera leaf gel according to the published procedure 11 with slight modifications. Aloe extract was able to essentially normalize lipid profiles provided further evidence for the application of aloe vera gel in the treatment of diabetes. Antibacterial activities and antioxidant capacity of aloe vera. From a case report to a randomized controlled trial, aloe is put to the test against cancer. Studies show that aloe vera can penetrate three epidermal layers of the skin. A typical gas chromatogram of extracts of aloe vera l. Antioxidant and antibacterial activity of aloe vera gel. The antioxidant activity of aloe vera extracts and reference compounds followed the order.
The first article published on the use of the aloe vera leaf in radiodermatitis was written by c. Aloe vera gel as a traditional and complementary method for. It is a disinfectant, antibiotic, antimicrobial, germicidal, antibacterial, antiseptic, anti fungal, and antiviral. Phytochemical and therapeutic profile of aloe vera informatics. The antifungal activity was determined by the agarwell. The first method was developed in a regular reverse phase chromatographic system using a particulate reverse phase c18 column. Jan 09, 2019 a study assessed the antioxidant activity of aloe vera gel on colorectal mucosal biopsies. Aloe vera has enjoyed a long history as a herbal remedy and is most popular herbal plant. Aloe vera is one of the plants exhibiting multiple benefits and has gained considerable importance in. Aloe vera gel as a traditional and complementary method. Aloe vera gel powder was studied by administration in rats with dietinduced obesity at two doses 20 and 200mgkgday for. Chemical composition and antioxidant activity of aloe vera.
Aloe barbadensis miller or aloe vera, a semi tropical plant is one of the 250 species of aloe. Analytically, 95% ethanol is less effective than ethyl acetatediethyl ether or hexane in the case of fatty acids extractions. Biochemical composition and enzymatic activity of aloe. Determination of total phenolic content and antioxidant activity of ethanol extracts from aloe spp. Aloe vera has a long history as a medicinal plant with diverse therapeutic applications. The in vitro antioxidant activity showed that the tannins extract of aloe vera has a moderate antiradical activity.
Aloe vera has earned its name in many jamaican households as the magic plant often leading the treatment options for a plethora of body, hair and skin conditions because of its proven natural. Aloin and saponin and chemical omposition of volatile. Table 2 shows antioxidant activity of the four methanolic extracts from several parts of a. Antioxidant activity of the exudate from aloe barbadensis. Earlier studies have reported the antiinflammatory and antibacterial properties of aloe. Invitro antioxidant activity of aloe vera aloe barbadensis. Major value added products from aloe are gel and juice. Obesity is the most rampant nutritional disease and a rapidly growing human health problem globally. Materials and methods preparation of aqueous extract of aloe vera aloe vera plant was obtained from the department of agronomy, university of ibadan, ibadan, nigeria. This study determined biochemical composition and enzymatic activity of aloe vera leaves. The study showed that aloe vera juice has antimicrobial activity against m. It is also placed by most sources in the liliaceae family although it has been designated its own family, known as aloeaceae eshun. Determination of total phenolic content and antioxidant.
Pdf in vitro antioxidant activities of aloe vera leaf. Antiinflammatory activity of extracts from aloe vera gel. Abstractaloe vera has been used worldwide both for pharmaceutical, food, and cosmetic industries due to the plethora of biological activities of some of its metabolites. There is no guarantee of strength, purity, or safety of these products. Potential candidate in health management via modulation. Aloe vera has more healing properties than most any other plants or herbs on the planet. Evaluation of antioxidative activity and uv absorption. Chemical composition and biochemical activity of aloe vera. Its thick leaves supply water for the plant to survive long periods of drought3. Pdf antioxidant and antityrosinase activities of aloe. We studied the effects of aqueous, chloroform, and ethanol extracts of aloe vera gel on carrageenaninduced edema in the rat paw, and neutrophil migration into the peritoneal cavity stimulated by carrageenan. The anthraquinones and chro mones are responsible for the anticancer activity, anti. Jul 19, 20 the aim of this study was to identify, quantify, and compare the phytochemical contents, antioxidant capacities, and antibacterial activities of aloe vera lyophilized leaf gel lge and 95% ethanol leaf gel extracts elge using gcms and spectrophotometric methods.
Evaluation of the antifungal and antioxidant activities of. The extracts were prepared by the sequential cold maceration method by using hexane, ethyl acetate, methanol and distilled water as a solvent. The aim of this study was to explore the feasibility of using fresh. Aloe vera gel contains powerful antioxidants belonging to a. The results in t able 1 present the influence of aloe e xtract. Aloe vera not only possesses hypoglycaemic activity but is hypotensive, hepatoprotective and 6also blood purifier. Aloe vera has been one of the most widely used therapeutic plants throughout human.
Aloe vera is one of the plants considered to have a hypoglycemic effect and many diabetic subjects take the gel because of its hypoglycaemic effect5. Aloe was result of aloin, a bitter juice that dried to yellow powder shelton, 1991. Five genotypes of aloe vera leaves were analysed biochemically and enzymatically. Wheatgrass juice for ulcerative colitis a randomized, doubleblind, placebocontrolled trial found wheatgrass juice to be safe and effective in the treatment of an inflammatory bowel disease. A number of interesting articles have appeared giving quaint historical lore and scientific application of the aloe vera leaf for dermatologic purposes. Modere aloe vera is a liquid formulation containing a blend of pure aloe vera gel.
The determination of such parameters and the evaluation of consumer acceptability were helpful to determine the effectiveness of the postharvest treatment with aloe vera for a storage period of 15 days. Plants belonging to genus aloe particularly aloe vera a. The sterile nutrient agar plates and potato dextrose agar plates were prepared. This study was conducted to determine chemical composition and biochemical activity of a.
The result of the main constituents of the tav were. Aloe barbadensis miller is a perennial succulent xerophyte, which develops water storage tissue in the leaves to survive in dry areas of low or erratic rainfall. University of sarajevo, faculty of science, department of chemistry, zmaja od bosne 3335, sarajevo, bih 3 extract. Aloe vera is a traditional medicinal plant that is harvest in south area ofiran and other regions. Chemical and physical properties of aloe vera aloe. A recent report has shown that the organic extracts of. Aloe vera is used in variety of skin ailments such as mild cuts, insect stings, bruises, poison ivy and eczema.
Full length research article consumption of aqueous. Preparation of the gel fresh aloe vera leaves were collected 14 kg from the municipality of apaxco, state of mex. Anthraquinotes derivatives in aloe vera gel play an important role in the treatment of tumors, diabetes, ulcer and cancer. It is a valuable ingredient in food, pharmaceutical and cosmetic industries although scientific evidence of its cosmetic and. Aloe vera is a dietary supplement and not a regulated drug. The innermost part of the leaf is a clear, soft, moist, and slippery tissue that consists of large thinwalled parenchyma cells in which water is held in the form of a viscous mucilage. Biochemical composition and enzymatic activity of aloe vera.
This study aims to determine phytochemical content, antioxidant activity and tyrosinase inhibition activity of aloe vera rind avre and gel avge extract. Component and application aloe vera plant in medicine. The disc diffusion method was used to test the antimicrobial activity. The percent inhibition by aloe vera ranged from 76. Full length research article consumption of aqueous extract. The lowest content of phenolic and flavonoid compounds was observed in. Ligin this cellulose substance is found in the gel has no known medical properties except it posses the property of penetrating the human skin. Antimicrobial activity and phytochemical screening of aloe. Supporting evidence for the antidiabetic activity of aloe vera was also reported from an animal study by korean investigators. Vera juice possessed stronger radical scavenging activity than that of aloe vera powder, and the antioxidative effect of aloe vera extracts was correlated to its development stage 12. The aim of this study was to investigate whether the extracts of aloe vera gel showed antiinflamma tory activity and to analyze some of its chemical constituents. Aloe vera has been described in writings in various cultures and as far back as egyptians, greek and roman eras. Preparation of the gel fresh aloe vera leaves were collected 14 kg from the municipality of apaxco, state of mex ico, in march, 1990. High polysaccharide aloe vera gel may improve absorption of other botanical herbs and vitamins.
The efficacy of the aloe gel checked in hyperlipidemic type 2 diabetic patients showed reduction in total cholesterol and ldl levels significantly huseini et. Figure 1 the active components of aloe include anthraquinones, chromones, polysaccharides, and enzymes. Keeping this fact in view, the resent study was undertaken to isolate the phenolic anthroquinones from aloe vera leaf gel. Chemical and physical properties of aloe vera aloe barbadensis. Aloe vera is highly produced in bangladesh, australia, the dominican republic, cuba, mexico, china, jamaica, india, south africa and kenya. Aloe vera is the oldest medicinal plant ever known and the most applied medicinal plant worldwide. Emodin hydroxyanthraquinones from aloe vera leaves has antineuroectodermal tumor activity both in vitro and vivo. Scientific investigations on aloe vera have gained more attention over the last several decades due to its reputable medicinal properties. Aloe vera is well known for its succulent leaves and.